Be sure that the application you are troubleshooting is NOT running. If it is, quit it.

In this example we are looking for InDesign related files, but some files may be used multiple applications and be named differently.

With your Home Library open, navigate to Caches, and look for related Adobe files.

In this example we are looking for InDesign related files, but some files may be used multiple applications and be named differently.

Select any suspect/related Cache files, and drag them to the trash and delete them.

What are Cache files? They are simply helper files that let applications remember and play back settings and preferences faster. They do not contain any saved user data, and are safe to delete!